Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | GAA | P10253 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | CASP3 | P42574 | 1/20 | 0.56 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.56 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.56 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28273734 | 0.80 | MEN1 (0.88) | MAPTALDH1A1GAAMEN1KMT2A | |
| SCHEMBL11641875 | 0.77 | NPSR1 (1.00) | MAPTALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL9062442 | 0.77 | GAA (0.59) | MAPTALDH1A1GAAMEN1KMT2A | |
| SCHEMBL7555562 | 0.77 | MAPT (0.62) | MAPTMEN1KMT2ALMNAKDM4E | |
| SCHEMBL9751392 | 0.76 | MAPT (0.59) | MAPTALDH1A1GAAMEN1KMT2A | |
| SCHEMBL12476809 | 0.76 | MEN1 (0.97) | MAPTALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL4863845 | 0.75 | MEN1 (0.67) | MAPTALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL22217664 | 0.75 | MEN1 (0.78) | MAPTALDH1A1GAAMEN1KMT2A | |
| SCHEMBL9051246 | 0.74 | HTR2C (0.70) | MAPTGAAMEN1KMT2ANPSR1 | |
| SCHEMBL7558694 | 0.74 | KDR (0.59) | MAPTALDH1A1GAAKMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002055661-A2 | FATTY ACID SYNTHASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-07-18 | — | — | WO | claimed |
| WO-2002055661-A2 | FATTY ACID SYNTHASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-07-18 | — | — | WO | disclosed |