Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10732292 | 0.79 | KDM4E (0.42) | KDM4EMEN1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL10830005 | 0.75 | ADRA2A (0.39) | KDM4EMEN1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL4459404 | 0.74 | KMT2A (0.51) | KDM4EMEN1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL11563119 | 0.74 | KDM4E (0.41) | KDM4EMEN1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL10830702 | 0.73 | CYP2D6 (0.38) | KDM4EMEN1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL10842038 | 0.73 | ADRA2A (0.40) | KDM4EMEN1CYP1A2CYP2D6CYP2C19 | |
| Cicletanine SCHEMBL637073 | 0.71 | MEN1 (0.36) | KDM4EMEN1CYP1A2CYP2D6CYP2C19 | |
| Cicletanine SCHEMBL16859315 | 0.71 | MEN1 (0.36) | KDM4EMEN1CYP1A2CYP2D6CYP2C19 | |
| Cicletanine SCHEMBL6060344 | 0.71 | MEN1 (0.36) | KDM4EMEN1CYP1A2CYP2D6CYP2C19 | |
| Cicletanine SCHEMBL49794 | 0.71 | MEN1 (0.36) | KDM4EMEN1CYP1A2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5047537-A | Separation of isomers of furo (3,4-C) pyridine derivatives | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 1991-09-10 | — | — | US | disclosed |