SCHEMBL9751453

SCHEMBL9751453

[Na]Cc1cnccn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL980114 0.80
SCHEMBL1521573 0.78 HSP90AA1 (0.43)
SCHEMBL978915 0.75
SCHEMBL246396 0.74
SCHEMBL284256 0.74
SCHEMBL344601 0.74
SCHEMBL3112201 0.74
SCHEMBL12431 0.74
SCHEMBL291279 0.74
SCHEMBL7692978 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5004732-A Treatment of acne SOCIETE ANONYME DITE: L'OREAL (FR) 1991-04-02 US claimed
JP-2292266-A None JP disclosed
US-5019576-A Anticoagulants SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) 1991-05-28 US disclosed
US-5004732-A Treatment of acne SOCIETE ANONYME DITE: L'OREAL (FR) 1991-04-02 US disclosed
JP-H02292266-A PIPERAZINE DERIVATIVE, ITS PRODUCTION AND THERAPEUTIC COMPOSITION CONTAINING THE SAME SOC CONSEILS RECH APPL SCIENT SA (SCRAS) 1990-12-03 JP disclosed
US-4638005-A ELECTRON CARRIERS IN THE PHOTOENZYMATIC PRODUCTION OF HYDROGEN AND AMMONIA THE COCA-COLA COMPANY 1987-01-20 US disclosed
US-4183933-A TREATMENT OF MENTAL ILLNESS, NEUROSIS, BEHAVIORAL DISTURBANCES, INFLAMMATION, ANOREXIA, AND CARDIAC AND VASCULAR DISORDERS AB FERROSAN (SE) 1980-01-15 US disclosed