Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.66 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.66 |
| ▸ | CDK4 | P11802 | 1/20 | 0.64 |
| ▸ | CCND1 | P24385 | 1/20 | 0.64 |
| ▸ | GFER | P55789 | 1/20 | 0.64 |
| ▸ | AANAT | Q16613 | 1/20 | 0.61 |
| ▸ | ACHE | P22303 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | BLM | P54132 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27382648 | 0.90 | L3MBTL1 (0.65) | MEN1KMT2AMAPTGAAHPGD | |
| SCHEMBL7677886 | 0.88 | MEN1 (0.84) | MEN1KMT2AMAPTMTNR1AGFER | |
| SCHEMBL21255779 | 0.85 | KMT2A (0.69) | MEN1KMT2AMAPTMTNR1AGFER | |
| SCHEMBL9303476 | 0.85 | MEN1 (0.71) | MEN1KMT2AMAPTMTNR1AGFER | |
| SCHEMBL7849865 | 0.84 | MEN1 (0.74) | MEN1KMT2AMAPTMTNR1AGFER | |
| SCHEMBL6306640 | 0.84 | MAPT (0.61) | MEN1KMT2AMAPTLMNACYP1A2 | |
| SCHEMBL7089394 | 0.84 | MAPT (0.61) | MEN1KMT2AMAPTLMNACYP1A2 | |
| SCHEMBL12836579 | 0.83 | MEN1 (0.73) | MEN1KMT2AMAPTMTNR1AGFER | |
| Hydrochloric Acid SCHEMBL6306434 | 0.83 | MAPT (0.60) | MEN1KMT2AMAPTLMNACYP1A2 | |
| SCHEMBL761481 | 0.83 | MTNR1A (0.88) | MEN1KMT2AMAPTMTNR1AGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0375726-A4 | MELATONIN ANALOGUES | — | 1991-01-30 | — | — | EP | disclosed |
| EP-0375726-A1 | MELATONIN ANALOGUES | Whitby Research Incorporated (US) | 1990-07-04 | — | — | EP | disclosed |
| WO-1989001472-A1 | MELATONIN ANALOGUES | NELSON RESEARCH & DEVELOPMENT CO. (US) | 1989-02-23 | — | — | WO | disclosed |