SCHEMBL9751585

SCHEMBL9751585

O=S(=O)(O)c1cccc(N(Cl)Cl)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.52
TSHR P16473 3/20 0.52
HSD17B10 Q99714 2/20 0.52
TDP1 Q9NUW8 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.46
NAPRT Q6XQN6 1/20 0.38
PTPN11 Q06124 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
HSD17B1 P14061 2/20 0.36
HSD17B2 P37059 2/20 0.36
NSD2 O96028 1/20 0.36
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35
LMNA P02545 1/20 0.35
SNCA P37840 1/20 0.35
CA12 O43570 1/20 0.35
CA4 P22748 1/20 0.35
CA9 Q16790 1/20 0.35
SENP3 Q9H4L4 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10348034 0.80 NSD2 (0.54) ALDH1A1TSHRHSD17B10TDP1SMN1; SMN2
Hydrochloric Acid SCHEMBL27809968 0.78 NSD2 (0.53) ALDH1A1TSHRHSD17B10TDP1SMN1; SMN2
SCHEMBL5499811 0.78 NSD2 (0.53) ALDH1A1TSHRHSD17B10TDP1SMN1; SMN2
SCHEMBL151444 0.78 ALDH1A1 (0.70) ALDH1A1TSHRHSD17B10TDP1SMN1; SMN2
SCHEMBL1563586 0.78 ALDH1A1 (0.70) ALDH1A1TSHRHSD17B10TDP1SMN1; SMN2
SCHEMBL11238331 0.76 CRHBP (0.47) ALDH1A1TSHRHSD17B10TDP1SMN1; SMN2
SCHEMBL27364754 0.76 TSHR (0.47) ALDH1A1TSHRHSD17B10TDP1SMN1; SMN2
SCHEMBL6854169 0.76 ALDH1A1 (0.55) ALDH1A1TSHRHSD17B10TDP1SMN1; SMN2
SCHEMBL30302484 0.76 ALDH1A1 (0.55) ALDH1A1TSHRHSD17B10TDP1SMN1; SMN2
SCHEMBL27615258 0.76 ALDH1A1 (0.47) ALDH1A1TSHRHSD17B10TDP1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0429614-A1 AZOPHENYL COMPOUNDS. JAMES ROBINSON LTD (GB) 1991-06-05 EP claimed
CN-102566269-A Color component, color filter and display element JSR K K 2012-07-11 CN disclosed
CN-100462487-C Protein fiber spinning dope and its preparing method GUANQI LI (CN) 2009-02-18 CN disclosed
CN-1814870-A Protein fiber spinning dope and its preparing method LI GUANQI (CN) 2006-08-09 CN disclosed
WO-1990015850-A1 AZOPHENYL COMPOUNDS JAMES ROBINSON LIMITED (GB) 1990-12-27 WO disclosed