Diphenylether

Diphenylether

SCHEMBL9751631

Cc1cccc(-c2ccccc2)c1.c1ccc(Oc2ccccc2)cc1

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.53
TSHR P16473 2/20 0.50
LTA4H P09960 2/20 0.50
ACHE P22303 2/20 0.48
HPGD P15428 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47
PPARG P37231 1/20 0.47
PPARA Q07869 1/20 0.47
L3MBTL1 Q9Y468 2/20 0.46
HTT P42858 2/20 0.46
TDP1 Q9NUW8 1/20 0.46
GAA P10253 1/20 0.46
FFAR4 Q5NUL3 1/20 0.46
MAOB P27338 1/20 0.45
CYP1A2 P05177 2/20 0.43
CYP2C9 P11712 2/20 0.43
MAPK1 P28482 2/20 0.43
CYP2C19 P33261 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20022135 0.94 ALDH1A1 (0.53) ALDH1A1TSHRLTA4HACHEHPGD
SCHEMBL20022101 0.94 ALDH1A1 (0.53) ALDH1A1TSHRLTA4HACHEHPGD
SCHEMBL16361076 0.94 PPARG (0.52) ALDH1A1TSHRLTA4HACHEHPGD
SCHEMBL14885946 0.93 ALDH1A1 (0.56) ALDH1A1TSHRLTA4HPPARGPPARA
SCHEMBL20022117 0.93 ALDH1A1 (0.51) ALDH1A1TSHRLTA4HACHEHPGD
SCHEMBL20022123 0.92 ALDH1A1 (0.55) ALDH1A1TSHRLTA4HACHEHPGD
SCHEMBL20022091 0.92 ALDH1A1 (0.55) ALDH1A1TSHRLTA4HACHEHPGD
SCHEMBL20022119 0.90 ALDH1A1 (0.53) ALDH1A1TSHRLTA4HACHEHPGD
SCHEMBL11344045 0.89 ALDH1A1 (0.55) ALDH1A1ACHESMN1; SMN2RAB9APPARG
SCHEMBL5548340 0.88 ALDH1A1 (0.65) ALDH1A1TSHRLTA4HACHEL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0400066-A4 HEAT-TRANSFER FLUIDS AND PROCESS FOR PREPARING THE SAME 1991-03-20 EP disclosed
EP-0400066-A1 HEAT-TRANSFER FLUIDS AND PROCESS FOR PREPARING THE SAME THE DOW CHEMICAL COMPANY (US) 1990-12-05 EP disclosed
WO-1989007634-A1 HEAT-TRANSFER FLUIDS AND PROCESS FOR PREPARING THE SAME THE DOW CHEMICAL COMPANY (US) 1989-08-24 WO disclosed