SCHEMBL5548340

SCHEMBL5548340

Cc1cccc(Oc2ccc(-c3ccccc3)cc2)c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.65
HTT P42858 3/20 0.56
TDP1 Q9NUW8 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
GAA P10253 1/20 0.51
GFER P55789 2/20 0.51
MAPK1 P28482 1/20 0.51
FFAR4 Q5NUL3 2/20 0.50
ACHE P22303 1/20 0.50
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
GSTP1 P09211 1/20 0.48
CYP1A2 P05177 1/20 0.48
CYP2C9 P11712 1/20 0.48
CYP2C19 P33261 1/20 0.48
FFAR1 O14842 1/20 0.48
LMNA P02545 1/20 0.48
NPSR1 Q6W5P4 1/20 0.48
HSD17B1 P14061 1/20 0.48
HSD17B2 P37059 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL675770 0.94 ALDH1A1 (0.71) ALDH1A1HTTTDP1L3MBTL1GAA
SCHEMBL14885946 0.93 ALDH1A1 (0.56) ALDH1A1HTTTDP1L3MBTL1GAA
SCHEMBL20022101 0.91 ALDH1A1 (0.53) ALDH1A1HTTTDP1L3MBTL1GAA
SCHEMBL20022135 0.91 ALDH1A1 (0.53) ALDH1A1HTTTDP1L3MBTL1GAA
SCHEMBL16361076 0.90 PPARG (0.52) ALDH1A1HTTTDP1L3MBTL1GFER
SCHEMBL16938819 0.90 HTT (0.67) ALDH1A1HTTTDP1L3MBTL1GAA
Diphenylether SCHEMBL10909478 0.90 ALDH1A1 (0.70) ALDH1A1HTTTDP1L3MBTL1GAA
SCHEMBL441890 0.90 ALDH1A1 (0.70) ALDH1A1HTTTDP1L3MBTL1GAA
SCHEMBL20022117 0.89 ALDH1A1 (0.51) ALDH1A1HTTTDP1L3MBTL1GFER
Diphenylether SCHEMBL9751631 0.88 ALDH1A1 (0.53) ALDH1A1HTTTDP1L3MBTL1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180207628-A1 OXALIC ACID MONOAMIDE LIGAND, AND USES THEREOF IN COUPLING REACTION OF COPPER-CATALYZED ARYL HALOGEN SUBSTITUTE SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) 2018-07-26 US disclosed
US-20180207628-A1 OXALIC ACID MONOAMIDE LIGAND, AND USES THEREOF IN COUPLING REACTION OF COPPER-CATALYZED ARYL HALOGEN SUBSTITUTE SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) 2018-07-26 US disclosed
WO-2017012379-A1 OXALIC ACID MONOAMIDE LIGAND, AND USES THEREOF IN COUPLING REACTION OF COPPER-CATALYZED ARYL HALOGEN SUBSTITUTE 中国科学院上海有机化学研究所 2017-01-26 WO disclosed
US-7295802-B2 Image forming apparatus using a cleaning unit for preventing noises RICOH COMPANY, LTD (JP) 2007-11-13 US disclosed
US-20070110488-A1 IMAGE FORMING APPARATUS AND PROCESS CARTRIDE THEREFOR KABATA TOSHIYUKI 2007-05-17 US disclosed
US-7181156-B2 Image forming apparatus using a cleaning member for preventing noises and process cartridge therefor RICOH COMPANY, LTD. (JP) 2007-02-20 US disclosed
US-20050069357-A1 Image forming apparatus and process cartridge therefor RICOH COMPANY, LTD (JP) 2005-03-31 US disclosed
US-5561016-A HAVING PHOTOCONDUCTIVE LAYER CONTAINING CHARGE GENERATING MATERIAL, POLYVINYL BUTYRAL BINDER, CHARGE TRANSPORTING MATERIAL AND BIPHENYL(OR DERIVATIVE) ON ELECTROCONDUCTIVE SUPPORT RICOH COMPANY, LTD. (JP) 1996-10-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180207628-A1 OXALIC ACID MONOAMIDE LIGAND, AND USES THEREOF IN COUPLING REACTION OF COPPER-CATALYZED ARYL HALOGEN SUBSTITUTE AOC2, AOC1, AOC3 ALDH1A1 213/4885HTT 3183/4885TDP1 4699/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.