SCHEMBL975185

SCHEMBL975185

C=CCc1ccc(-c2ccc(C)s2)s1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT6 Q96LA8 1/20 0.38
PDE4B Q07343 2/20 0.38
PDE4D Q08499 2/20 0.38
MAPT P10636 3/20 0.35
NPC1 O15118 3/20 0.35
ALDH1A1 P00352 2/20 0.35
HSD17B10 Q99714 2/20 0.35
GFER P55789 1/20 0.35
ADRA1D P25100 2/20 0.34
CYP1A2 P05177 2/20 0.33
CYP3A4 P08684 2/20 0.33
CYP2C9 P11712 2/20 0.33
CYP2C19 P33261 2/20 0.33
TP53 P04637 2/20 0.33
THRB P10828 1/20 0.33
CYP2E1 P05181 1/20 0.32
CYP2C8 P10632 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2A6 P11509 1/20 0.32
CYP2B6 P20813 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL974768 0.88
SCHEMBL2784365 0.78 CYP2A6 (0.41) CYP3A4CYP2C9CYP2C19CYP2E1CYP2D6
SCHEMBL6292229 0.76 ALDH1A1 (0.34) MAPTALDH1A1CYP1A2CYP3A4TP53
SCHEMBL22115890 0.75 PRMT6 (0.48) PRMT6MAPTNPC1ALDH1A1HSD17B10
SCHEMBL20461843 0.75 PRMT6 (0.48) PRMT6MAPTNPC1ALDH1A1HSD17B10
SCHEMBL12362134 0.75 PRMT6 (0.43) PRMT6MAPTNPC1ALDH1A1HSD17B10
SCHEMBL14586198 0.74 PRMT6 (0.42) PRMT6MAPTNPC1ALDH1A1HSD17B10
SCHEMBL19262240 0.74 PRMT6 (0.47) PRMT6MAPTNPC1ALDH1A1HSD17B10
SCHEMBL14547865 0.74 PRMT6 (0.42) PRMT6MAPTNPC1ALDH1A1HSD17B10
SCHEMBL29764 0.73 NPC1 (0.52) PRMT6MAPTNPC1ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8475937-B2 Silicone composition and organic light-emitting diode DOW CORNING CORPORATION (US) 2013-07-02 US disclosed
EP-2262861-B1 SILICONE COMPOSITION AND ORGANIC LIGHT-EMITTING DIODE DOW CORNING (US) 2012-09-19 EP disclosed
US-20110017986-A1 Silicone Composition and Organic Light-Emitting Diode DOW CORNING CORPORATION 2011-01-27 US disclosed
EP-2262861-A1 SILICONE COMPOSITION AND ORGANIC LIGHT-EMITTING DIODE Dow Corning Corporation (US) 2010-12-22 EP disclosed
WO-2009120434-A1 SILICONE COMPOSITION AND ORGANIC LIGHT-EMITTING DIODE DOW CORNING CORPORATION (US) 2009-10-01 WO disclosed