Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | EPHX2 | P34913 | 8/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | CASP6 | P55212 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11071000 | 0.75 | KDM4E (0.65) | KDM4EEPHX2ALDH1A1CASP6SIGMAR1 | |
| SCHEMBL2730613 | 0.74 | EPHX2 (1.00) | EPHX2EPHX1 | |
| SCHEMBL2719520 | 0.74 | EPHX2 (1.00) | EPHX2EPHX1 | |
| SCHEMBL29955444 | 0.74 | KDM4E (0.59) | KDM4EEPHX2ALDH1A1CASP6SIGMAR1 | |
| SCHEMBL19046434 | 0.73 | KDM4E (0.77) | KDM4EALDH1A1CASP6SIGMAR1GAA | |
| SCHEMBL977989 | 0.73 | KDM4E (0.58) | KDM4EEPHX2ALDH1A1CASP6SIGMAR1 | |
| SCHEMBL1021506 | 0.72 | KDM4E (0.58) | KDM4EEPHX2ALDH1A1CASP6SIGMAR1 | |
| SCHEMBL975152 | 0.72 | CA12 (0.68) | EPHX2ALDH1A1SIGMAR1LMNA | |
| SCHEMBL931735 | 0.72 | BLM (0.41) | KDM4EEPHX2ALDH1A1NPSR1 | |
| SCHEMBL19229769 | 0.72 | EPHX2 (0.63) | EPHX2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011000945-A9 | AMINOALKAMIDES FOR USE IN THE TREATMENT OF INFLAMMATORY, DEGENERATIVE OR DEMYELINATING DISEASES OF THE CNS | NENSIUS RESEARCH A/S (DK) | 2011-04-07 | — | — | WO | claimed |
| WO-2011000945-A9 | AMINOALKAMIDES FOR USE IN THE TREATMENT OF INFLAMMATORY, DEGENERATIVE OR DEMYELINATING DISEASES OF THE CNS | NENSIUS RESEARCH A/S (DK) | 2011-04-07 | — | — | WO | disclosed |
| WO-2011000945-A2 | AMINOALKAMIDES FOR USE IN THE TREATMENT OF INFLAMMATORY, DEGENERATIVE OR DEMYELINATING DISEASES OF THE CNS | NENSIUS RESEARCH A/S (DK) | 2011-01-06 | — | — | WO | disclosed |