Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.51 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL977989 | 0.95 | KDM4E (0.58) | KDM4ESIGMAR1ALDH1A1CHRM5CHRM3 | |
| SCHEMBL1021506 | 0.94 | KDM4E (0.58) | KDM4ESIGMAR1ALDH1A1CHRM5CHRM3 | |
| SCHEMBL1899938 | 0.92 | KDM4E (0.54) | KDM4ESIGMAR1ALDH1A1CHRM5CHRM3 | |
| SCHEMBL983313 | 0.81 | SIGMAR1 (0.78) | KDM4ESIGMAR1CHRM5CHRM3EPHX1 | |
| SCHEMBL24322648 | 0.78 | SIGMAR1 (0.76) | KDM4ESIGMAR1ALDH1A1EPHX1GAA | |
| SCHEMBL974058 | 0.77 | SIGMAR1 (1.00) | KDM4ESIGMAR1CHRM5CHRM3EPHX1 | |
| SCHEMBL29955444 | 0.77 | KDM4E (0.59) | KDM4ESIGMAR1ALDH1A1EPHX1HTT | |
| SCHEMBL11063231 | 0.76 | SIGMAR1 (0.54) | KDM4ESIGMAR1ALDH1A1CHRM5CHRM3 | |
| SCHEMBL973523 | 0.76 | SIGMAR1 (1.00) | KDM4ESIGMAR1ALDH1A1CHRM5CHRM3 | |
| Hydrochloric Acid SCHEMBL5485542 | 0.75 | SIGMAR1 (0.52) | KDM4ESIGMAR1ALDH1A1CHRM5CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4478838-A | VASODILATOR AGENTS | HOKURIKU PHARMACEUTICAL CO., LTD. (JP) | 1984-10-23 | — | — | US | disclosed |
| EP-0083712-A1 | 1-(3,4,5-Trimethoxycinnamoyl)-4-aminocarbonylethyl-substituted piperazine derivatives and a process for the preparation thereof | Hokuriku Pharmaceutical Co.,Ltd (JP) | 1983-07-20 | — | — | EP | disclosed |