1-Hydroxy-2-Ethoxybenzene

1-Hydroxy-2-Ethoxybenzene

SCHEMBL9751925

C=CCOc1ccccc1OC(=O)NC.CCOc1ccccc1O

nearest known ligand 0.47

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIG1 P18858 1/20 0.45
ALDH1A1 P00352 6/20 0.45
ACHE P22303 1/20 0.45
GAA P10253 3/20 0.42
MAPT P10636 3/20 0.42
MAPK1 P28482 2/20 0.42
PGR P06401 1/20 0.42
PTGS1 P23219 1/20 0.42
HSD17B10 Q99714 1/20 0.42
L3MBTL1 Q9Y468 2/20 0.41
GLA P06280 1/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
LMNA P02545 4/20 0.41
CYP2D6 P10635 2/20 0.41
SLC22A1 O15245 1/20 0.41
CYP1A2 P05177 1/20 0.41
ADRB2 P07550 1/20 0.41
ADRB1 P08588 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8754763 0.89 ALDH1A1 (0.54) LIG1ALDH1A1ACHEGAAMAPK1
SCHEMBL9325544 0.84 ALDH1A1 (0.60) ALDH1A1ACHEGAAMAPTMAPK1
Eugenol SCHEMBL1879063 0.78 ALDH1A1 (0.60) ALDH1A1GAAMAPTPTGS1L3MBTL1
1-Allyloxy-2-Ethoxybenzene SCHEMBL11755537 0.78 HPGD (0.51) LIG1ALDH1A1MAPTMAPK1HSD17B10
SCHEMBL11667670 0.76 ALDH1A1 (0.56) ALDH1A1GAAMAPTL3MBTL1GLA
SCHEMBL92889 0.76 ALDH1A1 (0.61) ALDH1A1ACHEGAAMAPTMAPK1
1-Hydroxy-2-Allyloxybenzene SCHEMBL1562951 0.76 GAA (0.59) LIG1ALDH1A1GAAMAPTMAPK1
1-Hydroxy-2-Ethoxybenzene SCHEMBL11580144 0.75 GLA (0.53) ALDH1A1GAAMAPTMAPK1L3MBTL1
1-Hydroxy-2-Ethoxybenzene SCHEMBL27920897 0.74 GAA (0.53) ALDH1A1GAAMAPTMAPK1L3MBTL1
1-Hydroxy-2-Ethoxybenzene SCHEMBL28203721 0.74 GAA (0.57) ALDH1A1GAAMAPTMAPK1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0449975-A1 NON-TIN-BASED, LOW TOXICITY ANTI-FOULING AGENTS. BATTELLE MEMORIAL INSTITUTE (US) 1991-10-09 EP claimed