SCHEMBL92889

SCHEMBL92889

CNC(=O)Oc1ccccc1O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.61
GAA P10253 3/20 0.61
HSD17B10 Q99714 2/20 0.61
PGR P06401 1/20 0.61
PTGS1 P23219 1/20 0.61
MAPK1 P28482 1/20 0.61
ACHE P22303 1/20 0.61
TSHR P16473 2/20 0.48
CA1 P00915 2/20 0.48
CA2 P00918 2/20 0.48
TP53 P04637 1/20 0.48
LMNA P02545 3/20 0.45
JAK2 O60674 1/20 0.45
MAPT P10636 1/20 0.45
KMT2A Q03164 2/20 0.45
POLB P06746 1/20 0.45
CHRM2 P08172 1/20 0.41
CHRM4 P08173 1/20 0.41
CHRM5 P08912 1/20 0.41
CHRM1 P11229 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9125546 0.82 GAA (0.68) ALDH1A1GAAHSD17B10PGRPTGS1
SCHEMBL17514888 0.82 GAA (0.47) ALDH1A1GAAHSD17B10PGRPTGS1
SCHEMBL5510978 0.80 GAA (0.45) ALDH1A1GAAHSD17B10PGRPTGS1
SCHEMBL9324445 0.80 ALDH1A1 (0.66) ALDH1A1GAAHSD17B10PGRPTGS1
SCHEMBL8927729 0.80 ALDH1A1 (0.61) ALDH1A1GAAHSD17B10PGRPTGS1
SCHEMBL28023340 0.79 GAA (0.58) GAAMAPK1ACHETSHRCA1
SCHEMBL11772785 0.78 ALDH1A1 (0.59) ALDH1A1GAAHSD17B10PGRPTGS1
SCHEMBL29434522 0.78 ALDH1A1 (0.59) ALDH1A1GAAHSD17B10PGRPTGS1
SCHEMBL8927725 0.78 ACHE (0.59) ALDH1A1GAAHSD17B10PGRPTGS1
SCHEMBL29728939 0.78 ALDH1A1 (0.59) ALDH1A1GAAHSD17B10PGRPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4788324-A Preparation of o-(1-methoxy-2-chloro)-ethoxyphenyl N-methylcarbamate BASF AKTIENGESELLSCHAFT (DE) 1988-11-29 US claimed
EP-0183061-B1 PROCESS FOR THE PREPARATION OF O-(1 METHOXY-2 CHLORO) ETHOXYPHENYL N-METHYL CARBAMATE BASF Aktiengesellschaft (DE) 1988-03-16 EP claimed
US-4537986-A Preparation of pyrocatechol methylcarbamate BASF AKTIENGESELLSCHAFT (DE) 1985-08-27 US claimed
EP-0100940-B1 PROCESS FOR THE PREPARATION OF PYROCATECHIN-METHYL CARBONATE BASF Aktiengesellschaft (DE) 1985-05-02 EP claimed
US-20120122970-A1 INSECTICIDAL CARBAMATES EXHIBITING SPECIES-SELECTIVE INHIBITION OF ACETYLCHOLINESTERASE (AChE) VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY 2012-05-17 US disclosed
US-8129428-B2 Insecticidal carbamates exhibiting species-selective inhibition of acetylcholinesterase (AChE) VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) 2012-03-06 US disclosed
US-20090068242-A1 INSECTICIDAL CARBAMATES EXHIBITING SPECIES-SELECTIVE INHIBITION OF ACETYLCHOLINESTERASE (AChE) VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY 2009-03-12 US disclosed
US-20050209117-A1 Complexing agent for treating metallic and plastic surfaces BASF AKTIENGESELLSCHAFT (DE) 2005-09-22 US disclosed
US-20050126427-A1 Polymer derivatives for treating metals BASF AKTIENGESELLSCHAFT (DE) 2005-06-16 US disclosed
CN-1620523-A Polymer derivatives for treating metals BASF AG (DE) 2005-05-25 CN disclosed
CN-1202086-C Halogenating agents MITSUI CHEMICAL CO LTD (JP) 2005-05-18 CN disclosed
CN-1483727-A Halogenating agents ������ѧ��ʽ���� 2004-03-24 CN disclosed
US-4788324-A Preparation of o-(1-methoxy-2-chloro)-ethoxyphenyl N-methylcarbamate BASF AKTIENGESELLSCHAFT (DE) 1988-11-29 US disclosed
US-4788324-A Preparation of o-(1-methoxy-2-chloro)-ethoxyphenyl N-methylcarbamate BASF AKTIENGESELLSCHAFT (DE) 1988-11-29 US disclosed
US-4537986-A Preparation of pyrocatechol methylcarbamate BASF AKTIENGESELLSCHAFT (DE) 1985-08-27 US disclosed
US-4537986-A Preparation of pyrocatechol methylcarbamate BASF AKTIENGESELLSCHAFT (DE) 1985-08-27 US disclosed
US-4537986-A Preparation of pyrocatechol methylcarbamate BASF AKTIENGESELLSCHAFT (DE) 1985-08-27 US disclosed
US-4143064-A Manufacture of β-halocetals or β-haloketals BASF AKTIENGESELLSCHAFT (DE) 1979-03-06 US disclosed
US-4140725-A CHEMICAL INTERMEDIATES FOR INSECTICIDES BASF AKTIENGESELLSCHAFT (DE) 1979-02-20 US disclosed
US-3962316-A PESTICIDES, O-(A-ALKOXY-B-HALO)-ETHOXYPHENYL-N-METHYL-CARBAMATE BASF AKTIENGESELLSCHAFT (DT) 1976-06-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090068242-A1 INSECTICIDAL CARBAMATES EXHIBITING SPECIES-SELECTIVE INHIBITION OF ACETYLCHOLINESTERASE (AChE) ACHE, BCHE, CHAT ALDH1A1 960/4885GAA 1339/4885HSD17B10 1503/4885
US-20120122970-A1 INSECTICIDAL CARBAMATES EXHIBITING SPECIES-SELECTIVE INHIBITION OF ACETYLCHOLINESTERASE (AChE) ACHE, BCHE, CHAT ALDH1A1 960/4885GAA 1339/4885HSD17B10 1503/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.