SCHEMBL9751980

SCHEMBL9751980

Cc1cccc(Cc2ccccc2O)c1O

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSPA5 P11021 1/20 0.64
TRPA1 O75762 2/20 0.56
KEAP1 Q14145 1/20 0.52
ALDH1A1 P00352 2/20 0.50
MAPT P10636 4/20 0.49
TP53 P04637 1/20 0.49
GAA P10253 1/20 0.49
MAPK1 P28482 1/20 0.49
HSD17B10 Q99714 1/20 0.49
MEN1 O00255 1/20 0.47
HTT P42858 1/20 0.47
KMT2A Q03164 1/20 0.47
ATM Q13315 1/20 0.45
GPR55 Q9Y2T6 1/20 0.43
CYP2D6 P10635 1/20 0.42
TSHR P16473 1/20 0.42
HIF1A Q16665 1/20 0.42
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17666372 0.98 HSPA5 (0.61) HSPA5TRPA1KEAP1ALDH1A1MAPT
SCHEMBL68936 0.89 ALDH1A1 (0.62) HSPA5TRPA1ALDH1A1HSD17B10ATM
SCHEMBL11126429 0.88 ALDH1A1 (0.54) HSPA5TRPA1ALDH1A1MAPTHSD17B10
SCHEMBL17666370 0.87 ALDH1A1 (0.59) HSPA5TRPA1ALDH1A1HSD17B10ATM
SCHEMBL1841639 0.85 HSPA5 (0.73) HSPA5TRPA1KEAP1ALDH1A1MAPT
SCHEMBL30874252 0.85 HSPA5 (0.80) HSPA5KEAP1ALDH1A1HSD17B10CYP2D6
SCHEMBL54577 0.85 HSPA5 (0.80) HSPA5KEAP1ALDH1A1HSD17B10CYP2D6
SCHEMBL5852506 0.85 HSPA5 (0.80) HSPA5KEAP1ALDH1A1HSD17B10CYP2D6
SCHEMBL1834878 0.84 HSPA5 (0.64) HSPA5TRPA1KEAP1ALDH1A1MAPT
SCHEMBL8583175 0.83 HSPA5 (0.76) HSPA5KEAP1ALDH1A1HSD17B10CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7860442-B2 Image fixing device having carbon lamp and reflector RICOH COMPANY, LTD. (JP) 2010-12-28 US disclosed
US-20080124152-A1 IMAGE FIXING DEVICE AND IMAGE FORMATION APPARATUS USING THE SAME RICOH COMPANY, LTD. (JP) 2008-05-29 US disclosed
EP-0439607-A4 NOVEL GLYOXYLATES AND HERBICIDAL AND PLANT GROWTH REGULANT ACTIVITY OF GLYOXYLATES 1991-12-04 EP disclosed
EP-0439607-A1 NOVEL GLYOXYLATES AND HERBICIDAL AND PLANT GROWTH REGULANT ACTIVITY OF GLYOXYLATES ISK BIOSCIENCES CORPORATION (US) 1991-08-07 EP disclosed
WO-1991000009-A1 NOVEL GLYOXYLATES AND HERBICIDAL AND PLANT GROWTH REGULANT ACTIVITY OF GLYOXYLATES FERMENTA ASC CORPORATION (US) 1991-01-10 WO disclosed
US-4979978-A Herbicidal 12H-dibenzo[d,g][1,3]dioxocin-6-carboxylic acids THE DOW CHEMICAL COMPANY (US) 1990-12-25 US disclosed
US-4976770-A POSTEMERGENCE, PREEMERGENCE HERBICIDES FERMENTA ASC CORPORATION (US) 1990-12-11 US disclosed
US-4380611-A Etherified methylol polyamide crosslinking agent, process for producing the same and resins crosslinked therewith COOK PAINT AND VARNISH COMPANY (US) 1983-04-19 US disclosed