SCHEMBL9751994

SCHEMBL9751994

O=[C]C1Oc2ccccc2Cc2ccccc2O1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 5/20 0.50
MAOB P27338 5/20 0.50
NISCH Q9Y2I1 1/20 0.36
TSHR P16473 2/20 0.35
HPGD P15428 1/20 0.35
HDAC4 P56524 1/20 0.34
HDAC7 Q8WUI4 1/20 0.34
HDAC5 Q9UQL6 1/20 0.34
CA2 P00918 2/20 0.33
CYP1A2 P05177 1/20 0.33
HTR2A P28223 1/20 0.33
NFKB1 P19838 1/20 0.33
NFKB2 Q00653 1/20 0.33
RELA Q04206 1/20 0.33
KDM4E B2RXH2 1/20 0.33
ADORA3 P0DMS8 1/20 0.33
AR P10275 1/20 0.33
CYP19A1 P11511 1/20 0.33
HSD17B10 Q99714 1/20 0.33
ACSL1 P33121 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3693844 0.83 CA2 (0.36) MAOAMAOBNISCHHPGDCA2
SCHEMBL16320192 0.81 NISCH (0.49) MAOAMAOBNISCHTSHRHPGD
SCHEMBL9752832 0.80 MAOA (0.50) MAOAMAOBNISCHTSHRHPGD
SCHEMBL2653890 0.72 HPGD (0.41) MAOAMAOBNISCHTSHRHPGD
Xanthene SCHEMBL1258507 0.71 MAOA (0.74) MAOAMAOBCYP1A2ACSL1
SCHEMBL9327125 0.71 POLB (0.56) MAOAMAOBNISCHTSHRHPGD
SCHEMBL95677 0.69 CA2 (0.44) NISCHCA2CHRM2CHRM4CHRM5
Hydrochloric Acid SCHEMBL9751989 0.69 POLB (0.55) MAOAMAOBNISCHTSHRHPGD
SCHEMBL9751988 0.69 MAOA (0.47) MAOAMAOBNISCHTSHRHPGD
SCHEMBL9751996 0.69 NISCH (0.53) MAOAMAOBNISCHTSHRHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0439607-A4 NOVEL GLYOXYLATES AND HERBICIDAL AND PLANT GROWTH REGULANT ACTIVITY OF GLYOXYLATES 1991-12-04 EP disclosed
EP-0439607-A1 NOVEL GLYOXYLATES AND HERBICIDAL AND PLANT GROWTH REGULANT ACTIVITY OF GLYOXYLATES ISK BIOSCIENCES CORPORATION (US) 1991-08-07 EP disclosed