Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.58 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.58 |
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9329661 | 0.87 | GABRA1 (0.58) | GABRA1GABRB2TSHRPOLBHPGD | |
| SCHEMBL9838282 | 0.86 | GABRA1 (0.54) | GABRA1GABRB2TSHRPOLBHPGD | |
| SCHEMBL2979477 | 0.85 | TSHR (0.67) | GABRA1GABRB2TSHRPOLBHPGD | |
| SCHEMBL8518211 | 0.82 | TSHR (0.44) | GABRA1GABRB2TSHRPOLBHPGD | |
| SCHEMBL18774937 | 0.79 | GABRA1 (0.54) | GABRA1GABRB2TSHRPOLBHPGD | |
| SCHEMBL29027348 | 0.79 | GABRA1 (0.54) | GABRA1GABRB2TSHRPOLBHPGD | |
| SCHEMBL20319876 | 0.78 | TSHR (0.62) | GABRA1GABRB2TSHRPOLBHPGD | |
| SCHEMBL10696250 | 0.78 | GABRA1 (0.52) | GABRA1GABRB2TSHRPOLBHPGD | |
| SCHEMBL296591 | 0.77 | TSHR (0.68) | GABRA1GABRB2TSHRPOLBHPGD | |
| SCHEMBL29860994 | 0.77 | TSHR (0.68) | GABRA1GABRB2TSHRPOLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0439607-A4 | NOVEL GLYOXYLATES AND HERBICIDAL AND PLANT GROWTH REGULANT ACTIVITY OF GLYOXYLATES | — | 1991-12-04 | — | — | EP | disclosed |
| EP-0439607-A1 | NOVEL GLYOXYLATES AND HERBICIDAL AND PLANT GROWTH REGULANT ACTIVITY OF GLYOXYLATES | ISK BIOSCIENCES CORPORATION (US) | 1991-08-07 | — | — | EP | disclosed |