Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | GPR183 | P32249 | 9/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.40 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9390893 | 0.86 | CA12 (0.54) | ESR1ESR2MAOBRAB9A | |
| SCHEMBL14546443 | 0.86 | CA12 (0.54) | ESR1ESR2MAOBRAB9A | |
| SCHEMBL9411957 | 0.85 | CYP1A2 (0.50) | MAOAMAOBMAPTALDH1A1CYP1A2 | |
| SCHEMBL9411954 | 0.85 | CYP1A2 (0.50) | MAOAMAOBMAPTALDH1A1CYP1A2 | |
| SCHEMBL9551400 | 0.85 | HSD11B1 (0.50) | GPR183MAOAMAOBMAPTALDH1A1 | |
| SCHEMBL9551421 | 0.85 | MAPT (0.47) | MAOAMAOBMAPTALDH1A1CYP1A2 | |
| SCHEMBL1711201 | 0.84 | LMNA (0.47) | MAOAMAOBMAPTALDH1A1CYP1A2 | |
| SCHEMBL7882197 | 0.84 | LMNA (0.47) | MAOAMAOBMAPTALDH1A1CYP1A2 | |
| SCHEMBL10381850 | 0.82 | F3 (0.55) | GPR183MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13967398 | 0.81 | KDM4E (0.53) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0449884-A4 | DERIVATIVES OF TETRAPEPTIDES AS CCK AGONISTS | — | 1991-10-30 | — | — | EP | disclosed |
| EP-0449884-A1 | DERIVATIVES OF TETRAPEPTIDES AS CCK AGONISTS | ABBOTT LABORATORIES (US) | 1991-10-09 | — | — | EP | disclosed |
| WO-1990006937-A1 | DERIVATIVES OF TETRAPEPTIDES AS CCK AGONISTS | ABBOTT LABORATORIES (US) | 1990-06-28 | — | — | WO | disclosed |