Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.54 |
| ▸ | DRD3 | P35462 | 2/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9776821 | 0.81 | MTNR1A (0.51) | ACHE | |
| SCHEMBL10447740 | 0.80 | DRD2 (0.58) | DRD2DRD3ACHE | |
| Hydrochloric Acid SCHEMBL10447759 | 0.79 | DRD2 (0.57) | DRD2DRD3ACHE | |
| SCHEMBL9776895 | 0.78 | DRD3 (0.50) | DRD2DRD3ACHE | |
| SCHEMBL2463176 | 0.78 | MTNR1A (0.60) | ACHE | |
| SCHEMBL9776892 | 0.77 | DRD2 (0.49) | DRD2DRD3 | |
| SCHEMBL2246315 | 0.76 | CYP1A2 (0.54) | — | |
| SCHEMBL9776896 | 0.76 | DRD2 (0.64) | DRD2DRD3 | |
| SCHEMBL2245582 | 0.76 | BAZ2B (0.64) | — | |
| SCHEMBL1673429 | 0.76 | BAZ2B (0.69) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5053430-A | For treating schizophrenia | BOEHRINGER INGELHEIM KG (DE) | 1991-10-01 | — | — | US | disclosed |
| EP-0435988-A1 | 2-AMINO-7-CARBAMOYL-1,2,3,4-TETRAHYDRONAPHTHALENES, PROCESS FOR PREPARING THEM AND THEIR USE AS DRUGS | BOEHRINGER INGELHEIM KG (DE) | 1991-07-10 | — | — | EP | disclosed |
| WO-1991001297-A1 | 2-AMINO-7-CARBAMOYL-1,2,3,4-TETRAHYDRONAPHTHALENES, PROCESS FOR PREPARING THEM AND THEIR USE AS DRUGS | BOEHRINGER INGELHEIM KG (DE) | 1991-02-07 | — | — | WO | disclosed |
| EP-0361300-A1 | Use of 2,7 diamino-1,2,3,4-tetrahydronaphthalenes as drugs, 2,7 diamino-1,2,3,4-tetrahydronaphthalenes as well as processes for their preparation | BOEHRINGER INGELHEIM KG (DE) | 1990-04-04 | — | — | EP | disclosed |