Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 3/20 | 0.54 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.43 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 2/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | GHSR | Q92847 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5204177 | 1.00 | KEAP1 (0.54) | KEAP1NFE2L2MAPTDPP8DPP7 | |
| SCHEMBL7197034 | 0.87 | KEAP1 (0.40) | KEAP1NFE2L2HPGDNPC1MEN1 | |
| SCHEMBL7343165 | 0.86 | MAPT (0.58) | MAPTDPP8DPP7ANPEPDPP4 | |
| SCHEMBL25003569 | 0.84 | KEAP1 (0.56) | KEAP1NFE2L2MAPTDPP8DPP7 | |
| SCHEMBL5612091 | 0.83 | MAPT (0.54) | KEAP1NFE2L2MAPTDPP8DPP7 | |
| SCHEMBL4413196 | 0.82 | KEAP1 (0.58) | KEAP1NFE2L2DPP8DPP7ANPEP | |
| SCHEMBL30600458 | 0.82 | KEAP1 (0.58) | KEAP1NFE2L2DPP8DPP7ANPEP | |
| SCHEMBL17073673 | 0.82 | KEAP1 (0.58) | KEAP1NFE2L2MAPTDPP8DPP7 | |
| SCHEMBL3925964 | 0.82 | KEAP1 (0.58) | KEAP1NFE2L2DPP8DPP7ANPEP | |
| SCHEMBL9331674 | 0.82 | KEAP1 (0.58) | KEAP1NFE2L2DPP8DPP7ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991000725-A2 | AMINO ACID ANALOG CCK ANTAGONISTS | ABBOTT LABORATORIES (US) | 1991-01-24 | — | — | WO | disclosed |