Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.43 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NOS3 | P29474 | 2/20 | 0.41 |
| ▸ | NOS2 | P35228 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9737107 | 0.76 | TAAR1 (0.56) | TAAR1IDO1CTBP2ALDH1A1ACHE | |
| SCHEMBL3482884 | 0.72 | TAAR1 (0.52) | TAAR1IDO1CTBP2ACHE | |
| Bethanidine SCHEMBL374640 | 0.71 | NPC1 (0.46) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL29459538 | 0.71 | TAAR1 (0.60) | TAAR1IDO1ALDH1A1ACHE | |
| SCHEMBL1263547 | 0.71 | TAAR1 (0.60) | TAAR1IDO1ALDH1A1ACHE | |
| SCHEMBL30000562 | 0.71 | TAAR1 (0.60) | TAAR1IDO1ALDH1A1ACHE | |
| SCHEMBL12996465 | 0.71 | TAAR1 (0.50) | TAAR1IDO1CTBP2ACHE | |
| SCHEMBL15999389 | 0.71 | TAAR1 (0.50) | TAAR1IDO1CTBP2ACHE | |
| Dimethylamine SCHEMBL2646042 | 0.71 | TAAR1 (0.50) | TAAR1IDO1CTBP2RAB9AACHE | |
| SCHEMBL13329815 | 0.69 | L3MBTL1 (0.56) | CTBP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110009446-A1 | OLIGOMER-GUANIDINE CLASS CONJUGATES | NEKTAR THERAPEUTICS (US) | 2011-01-13 | — | — | US | claimed |
| WO-2009089053-A1 | OLIGOMER-GUANIDINE CLASS CONJUGATES | NEKTAR THERAPEUTICS AL, CORPORATION (US) | 2009-07-16 | — | — | WO | claimed |
| US-20110009446-A1 | OLIGOMER-GUANIDINE CLASS CONJUGATES | NEKTAR THERAPEUTICS (US) | 2011-01-13 | — | — | US | disclosed |
| WO-2009089053-A1 | OLIGOMER-GUANIDINE CLASS CONJUGATES | NEKTAR THERAPEUTICS AL, CORPORATION (US) | 2009-07-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110009446-A1 | OLIGOMER-GUANIDINE CLASS CONJUGATES | GMPS, OGT, GBA1 | TAAR1 1599/4885GRIN2D 1739/4885GRIN3B 519/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.