Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 5/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | HPGD | P15428 | 4/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28159299 | 0.66 | PDE10A (0.45) | PDE10ANPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL2787902 | 0.65 | PDE10A (0.35) | PDE10ANPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL20342557 | 0.62 | HDAC4 (0.48) | PDE10ANPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL29835415 | 0.62 | PDE10A (0.41) | PDE10ANPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL29966674 | 0.60 | NPC1 (0.63) | PDE10ANPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL29614829 | 0.60 | NPC1 (0.63) | PDE10ANPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL3076524 | 0.60 | NPC1 (0.63) | PDE10ANPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL29942654 | 0.60 | NPC1 (0.63) | PDE10ANPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL28695999 | 0.60 | HDAC4 (0.43) | PDE10ANPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL29184273 | 0.59 | L3MBTL1 (0.45) | PDE10ANPC1RAB9ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991000725-A2 | AMINO ACID ANALOG CCK ANTAGONISTS | ABBOTT LABORATORIES (US) | 1991-01-24 | — | — | WO | disclosed |