Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6979656 | 0.82 | TAAR1 (0.33) | TAAR1CHRM2CHRM1CHRNB2CHRM3 | |
| SCHEMBL8950647 | 0.78 | MAPT (0.45) | TAAR1CHRM2CHRM1CHRM3 | |
| SCHEMBL6853638 | 0.78 | CA12 (0.33) | — | |
| SCHEMBL9669770 | 0.78 | CYP1A2 (0.30) | — | |
| SCHEMBL1486243 | 0.78 | CMA1 (0.32) | TAAR1CHRM2CHRM1CHRNB2CHRM3 | |
| SCHEMBL7074719 | 0.78 | TAAR1 (0.34) | TAAR1 | |
| SCHEMBL7835653 | 0.77 | FFAR1 (0.43) | — | |
| SCHEMBL10752702 | 0.76 | CYP3A4 (0.43) | — | |
| SCHEMBL9137648 | 0.76 | TAAR1 (0.32) | TAAR1 | |
| SCHEMBL6203463 | 0.74 | IDO1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991010650-A1 | PIPERIDINE AND PYRROLIDINE DERIVATIVES | PFIZER LIMITED (GB) | 1991-07-25 | — | — | WO | disclosed |