Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | PNMT | P11086 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3047306 | 0.85 | TAAR1 (0.34) | TAAR1HRH3CA12CA1CA2 | |
| SCHEMBL1486243 | 0.81 | CMA1 (0.32) | TAAR1 | |
| SCHEMBL9669770 | 0.81 | CYP1A2 (0.30) | — | |
| SCHEMBL6853638 | 0.81 | CA12 (0.33) | CA12CA2CA3CA4CA6 | |
| SCHEMBL6203463 | 0.80 | IDO1 (0.42) | — | |
| SCHEMBL6979656 | 0.78 | TAAR1 (0.33) | TAAR1 | |
| SCHEMBL9752268 | 0.78 | TDP1 (0.33) | TAAR1 | |
| SCHEMBL1316541 | 0.78 | TAAR1 (0.55) | TAAR1PNMT | |
| SCHEMBL7317921 | 0.77 | LOXL2 (0.35) | LOXL2NCF1 | |
| SCHEMBL3861727 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030105073-A1 | Quinolone derivatives | CELLTECH R&D LIMITED (GB) | 2003-06-05 | — | — | US | disclosed |
| WO-2003035066-A1 | 2-AMINOQUINOLONE DERIVATIVES FOR USE AS IMPDH INHIBITORS | CELLTECH R & D LIMITED (GB) | 2003-05-01 | — | — | WO | disclosed |
| EP-0686625-B1 | ANTHRANILIC ACID DERIVATIVE | EISAI CO LTD (JP) | 1999-05-26 | — | — | EP | disclosed |
| US-5371247-A | Preparation of substituted ethenes | FINE ORGANICS LIMITED (GB) | 1994-12-06 | — | — | US | disclosed |
| EP-0466733-B1 | PREPARATION OF SUBSTITUTED ETHENES | FINE ORGANICS LTD (GB) | 1994-08-17 | — | — | EP | disclosed |
| EP-0466733-A1 | PREPARATION OF SUBSTITUTED ETHENES. | FINE ORGANICS LTD (GB) | 1992-01-22 | — | — | EP | disclosed |
| WO-1990012002-A1 | PREPARATION OF SUBSTITUTED ETHENES | FINE ORGANICS LIMITED (GB) | 1990-10-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030105073-A1 | Quinolone derivatives | IFNAR1, CBR1, IMPDH1 | TAAR1 1402/4885HRH3 259/4885ROCK2 2933/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.