Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 18/20 | 0.42 |
| ▸ | AGXT | P21549 | 9/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7235293 | 0.98 | IDO1 (0.43) | IDO1AGXTCYP3A4 | |
| SCHEMBL7074719 | 0.80 | TAAR1 (0.34) | — | |
| SCHEMBL3856257 | 0.78 | TSHR (0.33) | CYP3A4 | |
| SCHEMBL6979656 | 0.77 | TAAR1 (0.33) | — | |
| SCHEMBL1486243 | 0.77 | CMA1 (0.32) | CYP3A4 | |
| SCHEMBL9669770 | 0.77 | CYP1A2 (0.30) | CYP3A4 | |
| SCHEMBL6853638 | 0.77 | CA12 (0.33) | CYP3A4 | |
| SCHEMBL3857285 | 0.75 | ALDH1A1 (0.39) | CYP3A4 | |
| SCHEMBL4673253 | 0.73 | ALDH1A1 (0.36) | CYP3A4 | |
| SCHEMBL3850167 | 0.73 | ALDH1A1 (0.35) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1266887-B1 | Indenoindoline derivatives, their process of preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2005-08-17 | — | — | EP | disclosed |
| EP-1266887-A2 | Indenoindoline derivatives, their process of preparation and pharmaceutical compositions containing them | Les Laboratoires Servier (FR) | 2002-12-18 | — | — | EP | disclosed |