Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.45 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9752338 | 0.84 | SPHK1 (0.42) | SPHK1HSD11B2BRD4DDB1CRBN | |
| SCHEMBL9752336 | 0.82 | SPHK1 (0.51) | SPHK1HSD11B2BRD4CHRM2CHRM1 | |
| SCHEMBL10272352 | 0.82 | SPHK1 (0.54) | SPHK1HSD11B2BRD4CHRM2CHRM1 | |
| SCHEMBL10272353 | 0.82 | SPHK1 (0.54) | SPHK1HSD11B2BRD4CHRM2CHRM1 | |
| SCHEMBL14314018 | 0.82 | SPHK1 (0.54) | SPHK1HSD11B2BRD4CHRM2CHRM1 | |
| SCHEMBL25148798 | 0.78 | SPHK1 (0.48) | SPHK1HSD11B2BRD4CHRM2CHRM1 | |
| SCHEMBL11956429 | 0.78 | SPHK1 (0.48) | SPHK1HSD11B2BRD4CHRM2CHRM1 | |
| SCHEMBL10223487 | 0.77 | SPHK1 (0.47) | SPHK1HSD11B2BRD4CHRM2CHRM1 | |
| SCHEMBL11968694 | 0.76 | SPHK1 (0.45) | SPHK1BRD4CHRM2CHRM1CHRM3 | |
| SCHEMBL8416163 | 0.74 | SPHK1 (0.48) | SPHK1HSD11B2BRD4CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991000724-A1 | ALKYNYL AMINES THAT REGULATE CHOLINERGIC NEUROTRANSMISSION | ABBOTT LABORATORIES (US) | 1991-01-24 | — | — | WO | disclosed |