Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.51 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14314018 | 0.90 | SPHK1 (0.54) | SPHK1BRD4HSD11B2NR1H2HCRTR2 | |
| SCHEMBL10272352 | 0.90 | SPHK1 (0.54) | SPHK1BRD4HSD11B2NR1H2HCRTR2 | |
| SCHEMBL10272353 | 0.90 | SPHK1 (0.54) | SPHK1BRD4HSD11B2NR1H2HCRTR2 | |
| SCHEMBL25148798 | 0.85 | SPHK1 (0.48) | SPHK1BRD4HSD11B2NR1H2HCRTR2 | |
| SCHEMBL11956429 | 0.85 | SPHK1 (0.48) | SPHK1BRD4HSD11B2NR1H2HCRTR2 | |
| SCHEMBL10223487 | 0.84 | SPHK1 (0.47) | SPHK1BRD4HSD11B2HCRTR2CHRM2 | |
| SCHEMBL1833725 | 0.83 | SPHK1 (0.49) | SPHK1BRD4HSD11B2HCRTR2CHRM2 | |
| SCHEMBL6979603 | 0.83 | SPHK1 (0.49) | SPHK1BRD4HSD11B2HCRTR2CHRM2 | |
| SCHEMBL1833726 | 0.83 | SPHK1 (0.49) | SPHK1BRD4HSD11B2HCRTR2CHRM2 | |
| SCHEMBL9752318 | 0.82 | SPHK1 (0.45) | SPHK1BRD4HSD11B2CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991000724-A1 | ALKYNYL AMINES THAT REGULATE CHOLINERGIC NEUROTRANSMISSION | ABBOTT LABORATORIES (US) | 1991-01-24 | — | — | WO | disclosed |