Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9752360 | 1.00 | NAAA (0.58) | NAAALMNAMAPK1HPGDCES2 | |
| SCHEMBL6438579 | 0.84 | CNR1 (0.59) | — | |
| SCHEMBL12676690 | 0.81 | NAAA (0.66) | NAAALMNAMAPK1HPGDCES2 | |
| SCHEMBL1615778 | 0.81 | NAAA (0.66) | NAAALMNAMAPK1HPGDCES2 | |
| SCHEMBL12676604 | 0.81 | NAAA (0.66) | NAAALMNAMAPK1HPGDCES2 | |
| SCHEMBL4202619 | 0.81 | GLS (0.43) | PRMT5WDR77MTNR1AMTNR1BBCAT2 | |
| SCHEMBL20490805 | 0.81 | GLS (0.43) | PRMT5WDR77MTNR1AMTNR1BBCAT2 | |
| Hydrochloric Acid SCHEMBL21995191 | 0.79 | GLS (0.43) | PRMT5WDR77MTNR1AMTNR1BBCAT2 | |
| Hydrochloric Acid SCHEMBL21995188 | 0.79 | GLS (0.43) | PRMT5WDR77MTNR1AMTNR1BBCAT2 | |
| SCHEMBL13765364 | 0.79 | NAAA (0.58) | NAAALMNAMAPK1HPGDKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991000724-A1 | ALKYNYL AMINES THAT REGULATE CHOLINERGIC NEUROTRANSMISSION | ABBOTT LABORATORIES (US) | 1991-01-24 | — | — | WO | disclosed |