Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.32 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.30 |
| ▸ | PTP4A2 | Q12974 | 1/20 | 0.30 |
| ▸ | PTP4A1 | Q93096 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9752370 | 0.77 | TSHR (0.34) | TSHRCYP3A4TDP1MAPTCACNA1B | |
| SCHEMBL7927628 | 0.77 | ALDH1A1 (0.37) | TSHRCYP3A4MAPT | |
| SCHEMBL7921505 | 0.76 | — | — | |
| SCHEMBL177943 | 0.76 | CYP3A4 (0.48) | TSHRCYP3A4TDP1MAPTCACNA1B | |
| SCHEMBL7928598 | 0.74 | TSHR (0.41) | TSHRTDP1 | |
| SCHEMBL7792592 | 0.74 | TDP1 (0.31) | TDP1 | |
| SCHEMBL7512684 | 0.73 | CYP3A4 (0.46) | TSHRCYP3A4TDP1MAPTCACNA1B | |
| SCHEMBL9276745 | 0.73 | SMN1; SMN2 (0.40) | TSHRCYP3A4TDP1MAPTCACNA1B | |
| SCHEMBL7921531 | 0.73 | HTT (0.39) | — | |
| SCHEMBL7933420 | 0.72 | TET2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850929-B1 | Novel bis(mono- and diperoxy-oxalates) derived from dihydroperoxides and alkyl and alkylperoxy halooxalates | ATOFINA CHEM INC (US) | 2001-06-27 | — | — | EP | disclosed |
| US-5837782-A | POLYMERIZATION CATALYST | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1998-11-17 | — | — | US | disclosed |
| EP-0850929-A1 | Novel bis(mono- and diperoxy-oxalates) derived from dihydroperoxides and alkyl and alkylperoxy halooxalates | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1998-07-01 | — | — | EP | disclosed |