Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | MTOR | P42345 | 1/20 | 0.49 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.49 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.49 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ST6GAL1 | P15907 | 5/20 | 0.43 |
| ▸ | NT5E | P21589 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9083304 | 0.83 | POLB (0.44) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL383275 | 0.82 | LMNA (0.43) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL3789728 | 0.80 | LMNA (0.43) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL18740734 | 0.80 | LMNA (0.58) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL4667668 | 0.79 | LMNA (0.52) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL383426 | 0.79 | LMNA (0.42) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL11430667 | 0.77 | LMNA (0.64) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL11796922 | 0.77 | LMNA (0.64) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL5710025 | 0.75 | TYMP (0.62) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL10381791 | 0.74 | ADORA1 (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991000288-A1 | HYDROPHOBIC NUCLEIC ACID PROBE | CHIRON CORP (US) | 1991-01-10 | — | — | WO | disclosed |