Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.33 |
| ▸ | PREP | P48147 | 1/20 | 0.32 |
| ▸ | FAP | Q12884 | 1/20 | 0.32 |
| ▸ | AOC2 | O75106 | 1/20 | 0.30 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.30 |
| ▸ | KLK1 | P06870 | 1/20 | 0.30 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9752567 | 1.00 | POLB (0.42) | POLBNPSR1L3MBTL1TSHRPSMB1 | |
| SCHEMBL9752611 | 0.86 | POLB (0.48) | POLBNPSR1L3MBTL1TSHRPSMB1 | |
| SCHEMBL9752610 | 0.86 | POLB (0.48) | POLBNPSR1L3MBTL1TSHRPSMB1 | |
| SCHEMBL9752638 | 0.86 | POLB (0.48) | POLBNPSR1L3MBTL1TSHRPSMB1 | |
| SCHEMBL7199048 | 0.79 | POLB (0.43) | POLBNPSR1L3MBTL1TSHRPSMB1 | |
| SCHEMBL28003654 | 0.76 | ALDH1A1 (0.46) | NPSR1TSHRLMNASMN1; SMN2 | |
| SCHEMBL28003655 | 0.76 | ALDH1A1 (0.46) | NPSR1TSHRLMNASMN1; SMN2 | |
| SCHEMBL4122303 | 0.76 | POLB (0.47) | POLBNPSR1L3MBTL1TSHRPSMB1 | |
| SCHEMBL1381419 | 0.75 | POLB (0.46) | POLBNPSR1L3MBTL1TSHRPSMB1 | |
| SCHEMBL31544330 | 0.74 | MAOB (0.50) | L3MBTL1PSMB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991009848-A1 | PYRIDINONES USEFUL AS ANTIATHEROSCLEROTIC AGENTS | THE UPJOHN COMPANY (US) | 1991-07-11 | — | — | WO | claimed |
| WO-1991009848-A1 | PYRIDINONES USEFUL AS ANTIATHEROSCLEROTIC AGENTS | THE UPJOHN COMPANY (US) | 1991-07-11 | — | — | WO | disclosed |