Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.38 |
| ▸ | PREP | P48147 | 1/20 | 0.38 |
| ▸ | FAP | Q12884 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | AOC2 | O75106 | 1/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.31 |
| ▸ | KLK1 | P06870 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9752611 | 0.88 | POLB (0.48) | POLBNPSR1TSHRPSMB1PSMB5 | |
| SCHEMBL9752610 | 0.88 | POLB (0.48) | POLBNPSR1TSHRPSMB1PSMB5 | |
| SCHEMBL9752638 | 0.88 | POLB (0.48) | POLBNPSR1TSHRPSMB1PSMB5 | |
| SCHEMBL9752569 | 0.79 | POLB (0.42) | POLBNPSR1TSHRPSMB1PSMB5 | |
| SCHEMBL9752567 | 0.79 | POLB (0.42) | POLBNPSR1TSHRPSMB1PSMB5 | |
| SCHEMBL28003655 | 0.78 | ALDH1A1 (0.46) | NPSR1TSHRLMNASMN1; SMN2 | |
| SCHEMBL28003654 | 0.78 | ALDH1A1 (0.46) | NPSR1TSHRLMNASMN1; SMN2 | |
| SCHEMBL4122303 | 0.78 | POLB (0.47) | POLBNPSR1TSHRPSMB1PSMB5 | |
| SCHEMBL1381419 | 0.76 | POLB (0.46) | POLBNPSR1TSHRPSMB1L3MBTL1 | |
| SCHEMBL30874636 | 0.76 | POLB (0.42) | POLBNPSR1TSHRPSMB1PSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6639093-B2 | Reacting benzyl chloride with hydroxybenzoic acid | BAYER AKTIENGESELLSCHAFT (DE) | 2003-10-28 | — | — | US | disclosed |
| US-20030053964-A1 | Process for the preparation of hydroxybenzoic benzyl esters | BAYER AKTIENGESELLSCHAFT (DE) | 2003-03-20 | — | — | US | disclosed |
| EP-1249443-A2 | Process for the production of hydroxybenzoic acid benzyl esters | BAYER AG (DE) | 2002-10-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030053964-A1 | Process for the preparation of hydroxybenzoic benzyl esters | HAAO, HPD, HACL2 | POLB 504/4885NPSR1 3509/4885TSHR 3829/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.