Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL9752715 | 0.93 | L3MBTL1 (0.43) | L3MBTL1NPC1MITFLMNATP53 | |
| Water SCHEMBL9752767 | 0.86 | L3MBTL1 (0.47) | L3MBTL1NPC1MITFLMNATP53 | |
| SCHEMBL9752671 | 0.85 | L3MBTL1 (0.51) | L3MBTL1NPC1MITFLMNATP53 | |
| SCHEMBL31424843 | 0.76 | SMN1; SMN2 (0.46) | L3MBTL1NPC1MITFLMNATP53 | |
| SCHEMBL15911434 | 0.75 | NPC1 (0.43) | L3MBTL1NPC1LMNATP53RAB9A | |
| SCHEMBL9394796 | 0.75 | L3MBTL1 (0.51) | L3MBTL1NPC1MITFLMNATP53 | |
| SCHEMBL9752736 | 0.74 | L3MBTL1 (0.60) | L3MBTL1NPC1MITFLMNATP53 | |
| SCHEMBL9752728 | 0.74 | L3MBTL1 (0.50) | L3MBTL1NPC1MITFLMNATP53 | |
| SCHEMBL9752719 | 0.74 | L3MBTL1 (0.50) | L3MBTL1NPC1MITFLMNATP53 | |
| SCHEMBL9752571 | 0.74 | L3MBTL1 (0.50) | L3MBTL1NPC1MITFLMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991009848-A1 | PYRIDINONES USEFUL AS ANTIATHEROSCLEROTIC AGENTS | THE UPJOHN COMPANY (US) | 1991-07-11 | — | — | WO | claimed |
| WO-1991009848-A1 | PYRIDINONES USEFUL AS ANTIATHEROSCLEROTIC AGENTS | THE UPJOHN COMPANY (US) | 1991-07-11 | — | — | WO | disclosed |