Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.42 |
| ▸ | DUT | P33316 | 1/20 | 0.39 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | CDK4 | P11802 | 2/20 | 0.36 |
| ▸ | CCND1 | P24385 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31424843 | 0.89 | SMN1; SMN2 (0.46) | L3MBTL1NPC1MITFLMNATP53 | |
| SCHEMBL9394796 | 0.88 | L3MBTL1 (0.51) | L3MBTL1NPC1MITFLMNATP53 | |
| SCHEMBL9752736 | 0.86 | L3MBTL1 (0.60) | L3MBTL1NPC1MITFLMNATP53 | |
| SCHEMBL9752719 | 0.86 | L3MBTL1 (0.50) | L3MBTL1NPC1MITFLMNATP53 | |
| SCHEMBL9752571 | 0.86 | L3MBTL1 (0.50) | L3MBTL1NPC1MITFLMNATP53 | |
| SCHEMBL9752728 | 0.86 | L3MBTL1 (0.50) | L3MBTL1NPC1MITFLMNATP53 | |
| SCHEMBL9752572 | 0.85 | L3MBTL1 (0.44) | L3MBTL1NPC1MITFLMNATP53 | |
| SCHEMBL9752573 | 0.85 | L3MBTL1 (0.58) | L3MBTL1NPC1MITFLMNATP53 | |
| SCHEMBL9752675 | 0.84 | L3MBTL1 (0.51) | L3MBTL1NPC1MITFLMNATP53 | |
| SCHEMBL9752595 | 0.80 | L3MBTL1 (0.55) | L3MBTL1NPC1MITFLMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991009848-A1 | PYRIDINONES USEFUL AS ANTIATHEROSCLEROTIC AGENTS | THE UPJOHN COMPANY (US) | 1991-07-11 | — | — | WO | claimed |
| WO-1991009848-A1 | PYRIDINONES USEFUL AS ANTIATHEROSCLEROTIC AGENTS | THE UPJOHN COMPANY (US) | 1991-07-11 | — | — | WO | disclosed |