Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.40 |
| ▸ | DUT | P33316 | 2/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.37 |
| ▸ | PREP | P48147 | 1/20 | 0.36 |
| ▸ | FAP | Q12884 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9680970 | 0.85 | NPC1 (0.43) | POLBNPSR1L3MBTL1NPC1MITF | |
| SCHEMBL14488158 | 0.83 | POLB (0.46) | POLBNPSR1L3MBTL1NPC1MITF | |
| SCHEMBL200911 | 0.82 | NPC1 (0.41) | POLBNPSR1L3MBTL1NPC1MITF | |
| SCHEMBL9752736 | 0.78 | L3MBTL1 (0.60) | POLBNPSR1L3MBTL1NPC1MITF | |
| SCHEMBL9752595 | 0.78 | L3MBTL1 (0.55) | POLBNPSR1L3MBTL1NPC1MITF | |
| SCHEMBL9752573 | 0.77 | L3MBTL1 (0.58) | POLBNPSR1L3MBTL1NPC1MITF | |
| SCHEMBL2897376 | 0.75 | L3MBTL1 (0.53) | POLBNPSR1L3MBTL1NPC1MITF | |
| SCHEMBL9394796 | 0.74 | L3MBTL1 (0.51) | POLBNPSR1L3MBTL1NPC1MITF | |
| SCHEMBL21401230 | 0.74 | — | — | |
| SCHEMBL20704972 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991009848-A1 | PYRIDINONES USEFUL AS ANTIATHEROSCLEROTIC AGENTS | THE UPJOHN COMPANY (US) | 1991-07-11 | — | — | WO | claimed |
| WO-1991009848-A1 | PYRIDINONES USEFUL AS ANTIATHEROSCLEROTIC AGENTS | THE UPJOHN COMPANY (US) | 1991-07-11 | — | — | WO | disclosed |