Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | F2 | P00734 | 3/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.46 |
| ▸ | EDNRA | P25101 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 3/20 | 0.42 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.40 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4270202 | 0.80 | CA2 (0.52) | CYP1A2CYP2C19HTTHIF1ATDP1 | |
| SCHEMBL5508602 | 0.80 | CYP1A2 (0.64) | CYP1A2CYP2C19HTTHIF1ATDP1 | |
| SCHEMBL9455666 | 0.77 | CYP1A2 (0.57) | CYP1A2CYP2C19HTTHIF1ATDP1 | |
| SCHEMBL6416698 | 0.76 | CA2 (0.57) | CYP1A2CYP2C19HTTHIF1ATDP1 | |
| SCHEMBL30597369 | 0.76 | CYP1A2 (0.45) | CYP1A2CYP2C19HTTHIF1ATDP1 | |
| SCHEMBL19270962 | 0.76 | CYP1A2 (0.71) | CYP1A2CYP2C19HTTHIF1ATDP1 | |
| SCHEMBL9779598 | 0.75 | EDNRA (0.48) | CA2F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6254983 | 0.75 | CYP1A2 (0.41) | CYP1A2CYP2C19HTTHIF1ATDP1 | |
| SCHEMBL597354 | 0.75 | MMP2 (0.54) | F2 | |
| SCHEMBL319321 | 0.75 | MMP2 (0.54) | F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991010427-A2 | THE EFFECT OF TRANSGLUTAMINASE INHIBITION ON MICROFILARIAE DEVELOPMENT AND MACROFILARIAE VIABILITY | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1991-07-25 | — | — | WO | disclosed |
| WO-1989001512-A1 | A SPONGE ENZYME HAVING TRANSGLUTAMINASE-LIKE ACTIVITY | THE LIPOSOME COMPANY, INC. (US) | 1989-02-23 | — | — | WO | disclosed |