SCHEMBL9752701

SCHEMBL9752701

C=CC(=O)NC(C)(S)CC

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
TSHR P16473 3/20 0.38
MAPK1 P28482 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
ZDHHC20 Q5W0Z9 1/20 0.37
ZDHHC2 Q9UIJ5 1/20 0.37
GAA P10253 1/20 0.30
THRB P10828 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4909167 0.78 ALDH1A1 (0.44) ALDH1A1CYP3A4CYP2C9CYP2C19MEN1
SCHEMBL460924 0.78 ALDH1A1 (0.53) ALDH1A1CYP3A4CYP2C9CYP2C19MEN1
SCHEMBL1907643 0.78 ALDH1A1 (0.44) ALDH1A1CYP3A4CYP2C9CYP2C19MEN1
SCHEMBL18408604 0.78
Hydrogen Sulfide SCHEMBL28295812 0.77 ALDH1A1 (0.51) ALDH1A1CYP3A4CYP2C9CYP2C19MEN1
SCHEMBL28949902 0.77 ALDH1A1 (0.51) ALDH1A1CYP3A4CYP2C9CYP2C19MEN1
SCHEMBL17350190 0.77 ALDH1A1 (0.43) ALDH1A1CYP3A4CYP2C9CYP2C19MEN1
SCHEMBL8766001 0.76 ALDH1A1 (0.42) ALDH1A1CYP3A4CYP2C9CYP2C19MEN1
Bicarbonate SCHEMBL9854206 0.75 ALDH1A1 (0.54) ALDH1A1CYP3A4CYP2C9CYP2C19MEN1
SCHEMBL8772020 0.75 ALDH1A1 (0.42) ALDH1A1CYP3A4CYP2C9CYP2C19MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1991010498-A1 STRONGLY ACIDIC MICROPOROUS MEMBRANES FOR CATIONIC EXCHANGE GELMAN SCIENCES, INC. (US) 1991-07-25 WO claimed