Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.66 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.54 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9752686 | 0.84 | HRH3 (0.69) | HRH3SIGMAR1SLC6A4 | |
| SCHEMBL8938239 | 0.83 | HRH3 (0.66) | HRH3TRPV6SIGMAR1SMPD1SLC6A2 | |
| SCHEMBL8879793 | 0.82 | TRPV6 (0.47) | HRH3TRPV6SIGMAR1SLC6A2SLC6A4 | |
| SCHEMBL6807049 | 0.81 | HRH3 (0.63) | HRH3TRPV6SIGMAR1 | |
| SCHEMBL6807045 | 0.81 | HRH3 (0.63) | HRH3TRPV6SIGMAR1 | |
| SCHEMBL9372352 | 0.81 | HRH3 (0.63) | HRH3TRPV6SIGMAR1 | |
| SCHEMBL6802109 | 0.78 | HRH3 (0.68) | HRH3SIGMAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL15173715 | 0.78 | HRH3 (0.59) | HRH3TRPV6SIGMAR1 | |
| SCHEMBL9376275 | 0.77 | HRH3 (0.65) | HRH3TRPV6SIGMAR1 | |
| SCHEMBL9376281 | 0.77 | HRH3 (0.65) | HRH3TRPV6SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991010648-A1 | DIPHENYLSULPHOXIMINE MUSCARINIC RECEPTOR ANTAGONISTS | PFIZER LIMITED (GB) | 1991-07-25 | — | — | WO | disclosed |