Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.69 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.58 |
| ▸ | HTR1A | P08908 | 2/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8938433 | 0.85 | HRH3 (0.69) | HRH3SIGMAR1HTR1ASLC6A4ALDH1A1 | |
| SCHEMBL9752727 | 0.84 | HRH3 (0.66) | HRH3SIGMAR1SLC6A4 | |
| SCHEMBL6802079 | 0.82 | HRH3 (0.66) | HRH3SIGMAR1 | |
| SCHEMBL6802071 | 0.82 | HRH3 (0.66) | HRH3SIGMAR1 | |
| SCHEMBL6801436 | 0.80 | HRH3 (0.71) | HRH3SIGMAR1HTR1ASLC6A4 | |
| SCHEMBL5193849 | 0.78 | HRH3 (0.60) | HRH3SIGMAR1 | |
| SCHEMBL26024360 | 0.78 | HRH3 (0.60) | HRH3SIGMAR1 | |
| SCHEMBL10669091 | 0.78 | HRH3 (1.00) | HRH3SIGMAR1HTR1ASLC6A4 | |
| SCHEMBL8938428 | 0.77 | HRH3 (0.58) | HRH3SIGMAR1HTR1ASLC6A4 | |
| SCHEMBL17294993 | 0.76 | HRH3 (0.97) | HRH3SIGMAR1HTR1ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991010648-A1 | DIPHENYLSULPHOXIMINE MUSCARINIC RECEPTOR ANTAGONISTS | PFIZER LIMITED (GB) | 1991-07-25 | — | — | WO | disclosed |