Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | LIPA | P38571 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.34 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL5372441 | 1.00 | EPHX1 (0.53) | EPHX1SMN1; SMN2SSTR4GLAKDM4E | |
| Bicarbonate SCHEMBL1125852 | 0.98 | EPHX1 (0.52) | EPHX1SMN1; SMN2SSTR4GLAKDM4E | |
| Bicarbonate SCHEMBL6036898 | 0.97 | EPHX1 (0.55) | EPHX1SMN1; SMN2SSTR4GLAKDM4E | |
| Bicarbonate SCHEMBL8827972 | 0.97 | EPHX1 (0.55) | EPHX1SMN1; SMN2SSTR4GLAKDM4E | |
| Bicarbonate SCHEMBL5597464 | 0.97 | EPHX1 (0.55) | EPHX1SMN1; SMN2SSTR4GLAKDM4E | |
| Bicarbonate SCHEMBL28367894 | 0.97 | EPHX1 (0.55) | EPHX1SMN1; SMN2SSTR4GLAKDM4E | |
| Isobutane SCHEMBL28450845 | 0.91 | EPHX1 (0.50) | EPHX1SMN1; SMN2SSTR4GLAKDM4E | |
| Acetic Acid SCHEMBL4353702 | 0.90 | EPHX1 (0.53) | EPHX1SMN1; SMN2SSTR4GLAKDM4E | |
| Bicarbonate SCHEMBL28626633 | 0.89 | EPHX1 (0.48) | EPHX1SMN1; SMN2SSTR4GLAKDM4E | |
| SCHEMBL23174694 | 0.84 | EPHX1 (0.48) | EPHX1SMN1; SMN2SSTR4GLAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240392053-A1 | THERMOSETTING COMPOSITIONS BASED ON (METH)ACRYLATES AND PEROXODICARBONATES | DELO INDUSTRIE KLEBSTOFFE GMBH & CO. KGAA (DE) | 2024-11-28 | — | — | US | disclosed |
| EP-4396301-A1 | HEAT-CURING MASS BASED ON (METH)ACRYLATES AND PEROXODICARBONATES | DELO Industrie Klebstoffe GmbH & Co. KGaA (DE) | 2024-07-10 | — | — | EP | disclosed |
| WO-2023030763-A1 | HEAT-CURING MASS BASED ON (METH)ACRYLATES AND PEROXODICARBONATES | DELO INDUSTRIE KLEBSTOFFE GMBH & CO. KGAA (DE) | 2023-03-09 | — | — | WO | disclosed |
| US-8722279-B2 | Polyazole-containing composition | BASF SE (DE) | 2014-05-13 | — | — | US | disclosed |
| US-8669328-B2 | Composition comprising as the aqueous dispersion preferably (meth)acrylate polymers containing benzophenone in a mixture with (meth)acrylate polymers different therefrom and the use of said composition | EVONIK ROEHM GMBH (DE) | 2014-03-11 | — | — | US | disclosed |
| US-8399530-B2 | Polymer foams | BASF SE (DE) | 2013-03-19 | — | — | US | disclosed |
| US-20120225360-A1 | METHOD FOR OPERATING A FUEL CELL | BASF SE (DE) | 2012-09-06 | — | — | US | disclosed |
| US-20120189922-A1 | METHOD FOR OPERATING A FUEL CELL, AND A CORRESPONDING FUEL CELL | BASF SE (DE) | 2012-07-26 | — | — | US | disclosed |
| US-20120107712-A1 | METHOD FOR OPERATING A FUEL CELL, AND A CORRESPONDING FUEL CELL | BASF SE (DE) | 2012-05-03 | — | — | US | disclosed |
| US-20120094211-A1 | POLYAZOLE-CONTAINING COMPOSITION | BASF SE (DE) | 2012-04-19 | — | — | US | disclosed |
| US-20040106512-A1 | ccomplexes with transition metal; hydrogenation catalyst | BASF AKTIENGESELLSCHAFT (DE) | 2004-06-03 | — | — | US | disclosed |
| US-6733680-B2 | WATER INSOLUBLE POLYMER PREPARATIONS COMPRISING AT LEAST ONE POLYMER MADE UP OF HYDROPHILIC POLYMER SEGMENTS, SUCH AS POLYETHERS, AND HYDROPHOBIC POLYMER SEGMENTS, SUCH AS STYRENE UNITS | BASF AKTIENGESELLSCHAFT (DE) | 2004-05-11 | — | — | US | disclosed |
| US-20040077796-A1 | Water-absorbing agent, method for the production and the utilization thereof | BASF AKTIENGESELLSCHAFT (DE) | 2004-04-22 | — | — | US | disclosed |
| US-20040072941-A1 | Aqueous coating substance that is substantially or completely free of volatile organic substances, method for producing the same and the use thereof | BASF COATINGS GMBH (DE) | 2004-04-15 | — | — | US | disclosed |
| US-20020193539-A1 | Method for producing polyacrylates | TESA SE (DE) | 2002-12-19 | — | — | US | disclosed |
| US-20020121488-A1 | Use of particulate polymers as filter aids for aqueous liquids | BASF AKTIENGESELLSCHAFT (DE) | 2002-09-05 | — | — | US | disclosed |
| US-6245410-B1 | PLASTICS | BASF AKTIENGESELLSCHAFT (DE) | 2001-06-12 | — | — | US | disclosed |
| US-6174929-B1 | FOAMING AQUEOUS MIXTURE OF MONOETHYLENICALLY UNSATURATED MONOMERS CONTAINING ACID GROUPS, WHICH NEUTRALIZED, WITH OR WITHOUT MONOETHYLENICALLY UNSATURATED MONOMERS, CROSSLINKERS; SURFACTANTS, INITIATORS, DISPERSING GAS BUBBLES, POLYMERIZING | BASF AKTIENGESELLSCHAFT (DE) | 2001-01-16 | — | — | US | disclosed |
| US-5753741-A | QUARTZ SAND CRISTOBALITE FILLER, BATHROOOM AND KITCHEN FIXTURES | BLANCO GMBH & CO. KG (DE) | 1998-05-19 | — | — | US | disclosed |
| US-4879361-A | PAPERMAKING, FLOCCULATION, ABSORBTION | BASF AKTIENGESELLSCHAFT (DE) | 1989-11-07 | — | — | US | disclosed |