Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 3/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 9/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.33 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.33 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.33 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9753686 | 0.88 | MAPK14 (0.40) | MAPK14PTGS2KMT2AKDM5BPOLB | |
| SCHEMBL9753682 | 0.88 | MAPK14 (0.40) | MAPK14PTGS2KMT2AKDM5BPOLB | |
| SCHEMBL9752973 | 0.88 | MAPK14 (0.43) | MAPK14PTGS2KDM5BPTGS1CSNK1A1 | |
| SCHEMBL9753416 | 0.88 | POLB (0.37) | MAPK14PTGS2KMT2AKDM5BALDH1A1 | |
| SCHEMBL9753114 | 0.86 | MAPK14 (0.42) | MAPK14PTGS2KMT2AKDM5BALDH1A1 | |
| SCHEMBL9753119 | 0.86 | PTGS2 (0.36) | PTGS2KMT2AKDM5BALDH1A1POLB | |
| SCHEMBL9752970 | 0.84 | KDM5B (0.34) | MAPK14PTGS2KMT2AKDM5BALDH1A1 | |
| SCHEMBL9753314 | 0.84 | KDM5B (0.34) | MAPK14PTGS2KMT2AKDM5BALDH1A1 | |
| SCHEMBL9753644 | 0.84 | PTGS2 (0.36) | MAPK14PTGS2KMT2AKDM5BALDH1A1 | |
| SCHEMBL9753408 | 0.83 | POLB (0.39) | MAPK14PTGS2KDM5BALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991018903-A1 | PYRROLOPYRIDAZINE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-12 | — | — | WO | disclosed |