Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 10/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9753238 | 0.80 | HMGCR (0.54) | HMGCR | |
| SCHEMBL9753170 | 0.78 | MAPK14 (0.44) | — | |
| SCHEMBL10637080 | 0.77 | HMGCR (0.60) | HMGCR | |
| SCHEMBL10640255 | 0.77 | HMGCR (0.54) | HMGCR | |
| SCHEMBL10637810 | 0.76 | HMGCR (0.55) | HMGCR | |
| SCHEMBL9753315 | 0.75 | MAPK14 (0.39) | HMGCR | |
| SCHEMBL9752965 | 0.74 | MAPK14 (0.43) | — | |
| SCHEMBL10634559 | 0.74 | HMGCR (0.51) | HMGCR | |
| SCHEMBL9753005 | 0.73 | HMGCR (0.51) | HMGCR | |
| SCHEMBL9753353 | 0.72 | HMGCR (0.52) | HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991018903-A1 | PYRROLOPYRIDAZINE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-12 | — | — | WO | disclosed |