Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 4/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | RAF1 | P04049 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | GCGR | P47871 | 12/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9752919 | 0.88 | SMN1; SMN2 (0.43) | EGFRADORA2AADORA1GCGR | |
| SCHEMBL9753346 | 0.87 | GCGR (0.39) | MAPK14EGFRRAF1ADORA3ADORA2A | |
| SCHEMBL9753002 | 0.84 | TGFBR1 (0.36) | MAPK14EGFRADORA2AADORA1PTGS2 | |
| SCHEMBL9753098 | 0.83 | GCGR (0.40) | MAPK14EGFRRAF1ADORA3ADORA2A | |
| SCHEMBL9753315 | 0.83 | MAPK14 (0.39) | MAPK14EGFRRAF1ADORA3ADORA2A | |
| SCHEMBL9753402 | 0.82 | MAPK14 (0.46) | MAPK14EGFRRAF1ADORA3ADORA2A | |
| SCHEMBL9753419 | 0.82 | GRM2 (0.36) | MAPK14GCGR | |
| SCHEMBL9752965 | 0.79 | MAPK14 (0.43) | MAPK14EGFRRAF1ADORA3ADORA2A | |
| SCHEMBL9753334 | 0.78 | GCGR (0.38) | MAPK14GCGR | |
| SCHEMBL9753321 | 0.78 | MAPK14 (0.44) | MAPK14EGFRRAF1ADORA3ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991018903-A1 | PYRROLOPYRIDAZINE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-12 | — | — | WO | disclosed |