Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 2/20 | 0.40 |
| ▸ | GCGR | P47871 | 7/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.34 |
| ▸ | HMGCR | P04035 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9752949 | 1.00 | MAPK14 (0.40) | MAPK14GCGRPTGS2HMGCRESR1 | |
| SCHEMBL9752903 | 0.88 | MAPK14 (0.43) | MAPK14GCGRPTGS2HMGCRALDH1A1 | |
| SCHEMBL9752967 | 0.88 | MAPK14 (0.39) | MAPK14GCGRPTGS2HMGCRESR1 | |
| SCHEMBL9752968 | 0.88 | MAPK14 (0.39) | MAPK14GCGRPTGS2HMGCRESR1 | |
| SCHEMBL9753707 | 0.83 | GCGR (0.36) | MAPK14GCGRPTGS2HMGCRESR1 | |
| SCHEMBL9753703 | 0.83 | GCGR (0.36) | MAPK14GCGRPTGS2HMGCRESR1 | |
| SCHEMBL9753686 | 0.80 | MAPK14 (0.40) | MAPK14PTGS2 | |
| SCHEMBL9753682 | 0.80 | MAPK14 (0.40) | MAPK14PTGS2 | |
| SCHEMBL9753212 | 0.80 | MAPK14 (0.41) | MAPK14GCGRPTGS2HMGCRESR1 | |
| SCHEMBL9753213 | 0.80 | MAPK14 (0.41) | MAPK14GCGRPTGS2HMGCRESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991018903-A1 | PYRROLOPYRIDAZINE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-12 | — | — | WO | disclosed |