Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 6/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.35 |
| ▸ | HMGCR | P04035 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9753703 | 1.00 | GCGR (0.36) | GCGRPTGS2HMGCRNPC1RAB9A | |
| SCHEMBL9753207 | 0.90 | ALDH1A1 (0.40) | GCGRPTGS2HMGCRNPC1RAB9A | |
| SCHEMBL9752949 | 0.83 | MAPK14 (0.40) | GCGRPTGS2HMGCRALDH1A1MAPK10 | |
| SCHEMBL9752948 | 0.83 | MAPK14 (0.40) | GCGRPTGS2HMGCRALDH1A1MAPK10 | |
| SCHEMBL9753671 | 0.81 | PTGS2 (0.37) | PTGS2NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9753676 | 0.81 | PTGS2 (0.37) | PTGS2NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9752968 | 0.78 | MAPK14 (0.39) | GCGRPTGS2HMGCRMAPK10MAPK14 | |
| SCHEMBL9752967 | 0.78 | MAPK14 (0.39) | GCGRPTGS2HMGCRMAPK10MAPK14 | |
| SCHEMBL27346853 | 0.77 | PPARA (0.41) | GCGRPTGS2HMGCRNPC1RAB9A | |
| SCHEMBL9753373 | 0.77 | HMGCR (0.60) | PTGS2HMGCRALDH1A1ESR1CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991018903-A1 | PYRROLOPYRIDAZINE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-12 | — | — | WO | disclosed |
| CN-1056690-A | PYRROLOPYRIDAZINE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO (JP) | 1991-12-04 | — | — | CN | disclosed |