Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GCGR | P47871 | 9/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | HMGCR | P04035 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9752948 | 0.88 | MAPK14 (0.40) | MAPK14ALDH1A1GCGRPTGS2MAPK10 | |
| SCHEMBL9752949 | 0.88 | MAPK14 (0.40) | MAPK14ALDH1A1GCGRPTGS2MAPK10 | |
| SCHEMBL5101038 | 0.86 | MAPK14 (0.42) | MAPK14ALDH1A1GCGRPTGS2MAPK10 | |
| SCHEMBL9753207 | 0.82 | ALDH1A1 (0.40) | MAPK14ALDH1A1GCGRPTGS2MAPK10 | |
| SCHEMBL9753374 | 0.78 | GCGR (0.57) | MAPK14GCGR | |
| SCHEMBL3819361 | 0.78 | MAPK14 (0.44) | MAPK14ALDH1A1GCGRPTGS2 | |
| SCHEMBL9752928 | 0.78 | MAPK14 (0.43) | MAPK14ALDH1A1PTGS2 | |
| SCHEMBL9753393 | 0.77 | HMGCR (0.38) | ALDH1A1GCGRPTGS2ARHMGCR | |
| SCHEMBL9753397 | 0.76 | HMGCR (0.48) | ALDH1A1PTGS2HMGCR | |
| SCHEMBL9752921 | 0.76 | HMGCR (0.63) | ALDH1A1PTGS2HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991018903-A1 | PYRROLOPYRIDAZINE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-12 | — | — | WO | disclosed |