Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GCGR | P47871 | 9/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | AKT2 | P31751 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | STAT1 | P42224 | 1/20 | 0.34 |
| ▸ | HMGCR | P04035 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9753771 | 0.86 | GCGR (0.40) | PTGDR2GCGR | |
| SCHEMBL9753309 | 0.83 | MAPK14 (0.43) | PTGDR2GCGR | |
| SCHEMBL9753336 | 0.82 | MAPK14 (0.42) | GCGR | |
| SCHEMBL9752952 | 0.82 | GCGR (0.39) | GCGR | |
| SCHEMBL9752927 | 0.82 | PTGER1 (0.41) | PTGDR2AKT1AKT2DHODHHMGCR | |
| SCHEMBL9752983 | 0.81 | GCGR (0.43) | GCGR | |
| SCHEMBL9753720 | 0.81 | GCGR (0.38) | GCGR | |
| SCHEMBL9753406 | 0.81 | GCGR (0.38) | GCGR | |
| SCHEMBL9753408 | 0.80 | POLB (0.39) | AKT1AKT2POLBHMGCR | |
| SCHEMBL9753125 | 0.80 | GCGR (0.37) | PTGDR2GCGRPOLBHMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991018903-A1 | PYRROLOPYRIDAZINE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-12 | — | — | WO | disclosed |