Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 13/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.35 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.32 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.32 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.32 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9753771 | 0.84 | GCGR (0.40) | GCGRTGFBR1TGFBR2KDM5B | |
| SCHEMBL9753309 | 0.84 | MAPK14 (0.43) | GCGRTGFBR1TGFBR2KDM5B | |
| SCHEMBL9752952 | 0.83 | GCGR (0.39) | GCGRTGFBR1TGFBR2KDM5BCSNK1D | |
| SCHEMBL9753336 | 0.83 | MAPK14 (0.42) | GCGRTGFBR1TGFBR2KDM5BCSNK1D | |
| SCHEMBL9752983 | 0.82 | GCGR (0.43) | GCGRTGFBR1TGFBR2 | |
| SCHEMBL9753720 | 0.81 | GCGR (0.38) | GCGRTGFBR1TGFBR2KDM5BCSNK1D | |
| SCHEMBL9752958 | 0.81 | PTGDR2 (0.39) | GCGR | |
| SCHEMBL9753125 | 0.81 | GCGR (0.37) | GCGRKDM5B | |
| SCHEMBL9753314 | 0.79 | KDM5B (0.34) | KDM5B | |
| SCHEMBL9753426 | 0.79 | GCGR (0.40) | GCGRTGFBR1TGFBR2KDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991018903-A1 | PYRROLOPYRIDAZINE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-12 | — | — | WO | disclosed |