Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 4/20 | 0.41 |
| ▸ | DHODH | Q02127 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | AKT2 | P31751 | 1/20 | 0.36 |
| ▸ | HMGCR | P04035 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27349905 | 0.86 | PTGER1 (0.38) | PTGER1DHODHMEN1KMT2AKDM4E | |
| SCHEMBL9753357 | 0.84 | PTGER1 (0.36) | PTGER1DHODHMEN1KMT2AKDM4E | |
| SCHEMBL9753408 | 0.82 | POLB (0.39) | ALDH1A1AKT1AKT2HMGCR | |
| SCHEMBL9752958 | 0.82 | PTGDR2 (0.39) | DHODHPTGDR2AKT1AKT2HMGCR | |
| SCHEMBL9753363 | 0.82 | DHODH (0.38) | PTGER1DHODHKDM4EALDH1A1HMGCR | |
| SCHEMBL9753490 | 0.78 | POLB (0.34) | KMT2AHMGCR | |
| SCHEMBL9753491 | 0.78 | POLB (0.34) | KMT2AHMGCR | |
| SCHEMBL9752965 | 0.78 | MAPK14 (0.43) | PTGER1DHODHMEN1KMT2AALDH1A1 | |
| SCHEMBL9753311 | 0.75 | HMGCR (0.42) | ALDH1A1HMGCR | |
| SCHEMBL9753296 | 0.75 | HMGCR (0.51) | ALDH1A1HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991018903-A1 | PYRROLOPYRIDAZINE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-12 | — | — | WO | disclosed |