Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 20/20 | 0.47 |
| ▸ | PSEN2 | P49810 | 20/20 | 0.47 |
| ▸ | APH1B | Q8WW43 | 20/20 | 0.47 |
| ▸ | NCSTN | Q92542 | 20/20 | 0.47 |
| ▸ | APH1A | Q96BI3 | 20/20 | 0.47 |
| ▸ | PSENEN | Q9NZ42 | 20/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19723252 | 0.85 | POLQ (0.37) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL19723251 | 0.80 | MEN1 (0.40) | — | |
| SCHEMBL1208112 | 0.78 | MEN1 (0.37) | — | |
| SCHEMBL8801278 | 0.76 | ALDH1A1 (0.43) | — | |
| SCHEMBL17601353 | 0.75 | FSCN1 (0.39) | — | |
| SCHEMBL2432062 | 0.75 | FSCN1 (0.39) | — | |
| SCHEMBL22361186 | 0.75 | ABCB1 (0.39) | — | |
| SCHEMBL2116911 | 0.74 | PDCD1 (0.44) | — | |
| SCHEMBL2116607 | 0.73 | POLB (0.35) | — | |
| SCHEMBL6117734 | 0.72 | SHMT1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991008207-A1 | ARTHROPODICIDAL PYRAZOLINES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-06-13 | — | — | WO | disclosed |