Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TLR4 | O00206 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9470405 | 0.82 | TLR4 (0.43) | MEN1KMT2APOLBALDH1A1RAB9A | |
| SCHEMBL7634605 | 0.78 | CHRM2 (0.50) | MEN1KMT2AALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL20103471 | 0.76 | TLR4 (0.43) | MEN1KMT2APOLBALDH1A1RAB9A | |
| SCHEMBL24249958 | 0.75 | TLR4 (0.49) | MEN1KMT2APOLBALDH1A1RAB9A | |
| SCHEMBL1141761 | 0.75 | TLR4 (0.49) | MEN1KMT2APOLBALDH1A1RAB9A | |
| SCHEMBL17118109 | 0.75 | TLR4 (0.49) | MEN1KMT2APOLBALDH1A1RAB9A | |
| SCHEMBL7634499 | 0.73 | ALDH1A1 (0.44) | MEN1KMT2AALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL22640216 | 0.73 | MEN1 (0.46) | MEN1KMT2APOLBALDH1A1PKM | |
| SCHEMBL22640236 | 0.73 | MEN1 (0.46) | MEN1KMT2APOLBALDH1A1PKM | |
| SCHEMBL7639363 | 0.71 | ALDH1A1 (0.44) | MEN1KMT2AALDH1A1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991007378-A1 | CYCLOALKYL-SUBSTITUTED GLUTARAMIDE DIURETIC AGENTS | PFIZER LIMITED (GB) | 1991-05-30 | — | — | WO | disclosed |