Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LARS1 | Q9P2J5 | 4/20 | 0.62 |
| ▸ | MMP2 | P08253 | 2/20 | 0.53 |
| ▸ | MMP9 | P14780 | 1/20 | 0.53 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | CASR | P41180 | 1/20 | 0.47 |
| ▸ | GSR | P00390 | 1/20 | 0.45 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.45 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.45 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | TERT | O14746 | 3/20 | 0.43 |
| ▸ | TARS1 | P26639 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3049869 | 0.82 | LARS1 (0.69) | LARS1CASRTARS1 | |
| SCHEMBL30483895 | 0.81 | LARS1 (0.63) | LARS1MMP2MMP9CASRTARS1 | |
| SCHEMBL6248268 | 0.79 | LARS1 (0.68) | LARS1CASRTARS1 | |
| SCHEMBL12448217 | 0.79 | LARS1 (0.73) | LARS1CASRTARS1 | |
| SCHEMBL10062713 | 0.78 | LARS1 (0.42) | LARS1MMP2MMP9TERT | |
| SCHEMBL10029341 | 0.78 | LARS1 (0.42) | LARS1MMP2MMP9CASRTERT | |
| SCHEMBL18019131 | 0.77 | LARS1 (1.00) | LARS1TARS1 | |
| Lysine SCHEMBL16553020 | 0.77 | GSR (0.61) | MMP2MMP9LTA4HCASRGSR | |
| SCHEMBL28173973 | 0.77 | LARS1 (1.00) | LARS1TARS1 | |
| Hydrochloric Acid SCHEMBL27943608 | 0.77 | LARS1 (0.65) | LARS1MMP2MMP9LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991007378-A1 | CYCLOALKYL-SUBSTITUTED GLUTARAMIDE DIURETIC AGENTS | PFIZER LIMITED (GB) | 1991-05-30 | — | — | WO | claimed |